” I’m going to try the losartan at night and see if it works better that way. I can take all the pee pills during the day.”
The textbooks say that loasartan at 100mg is still 85% effective 24 hours later, but not at lower doses. But then again, depending on how bad the high BP is, 100mg may be more than needed and can lower the BP too much when it is at top strength, in the earliest hours after taking it.
My dose is 50mg but that dose is to be taken twice a day.
I just found the noon and bed time arrangement works well and kept to it.
The one thing I have learned about most medicines is that it is best to keep to a fairly strict timing regimen. The exact time is usually less important that keeping close to the same time each day, whatever that is. s better than taking the same medicine at hop scotch random times a day, as if “once a day” means only that as long as you at least take it “once a day” that is good enough. I don’t think so.
Arriving at what is a good standard dose for someone, using an initial period of trying a BP med, CANNOT be found in that intitial period if the medicine is taken at all kinds of different times of the day. The amount of the medicine that is active in the blood stream is too irregular if taking of the medicine is too irregular.
Taking our pills with consittent regularity as to the time of day is important to having them work as intended.
I have a sister in law who committed that patient “crime”, with disastrous results. She had more than one hospitalization because she was totally irregular with her medications. My brother and I and her doctors had to lecture her many times about how they could not get her meds right if she kept taking them willy nilly, whenever it suited her. A number of her blood readings (not just BP) were going from big escalations to major lows, with her rocking between sleepy all the time to not getting any sleep, and back and forth. There was nothing really wrong with her meds. She was the problem.
I worked with her in laying out her meds for the day in the morning, taking all the meds needed to be taken between then and the next morning, with the right doses taken out of the prescritpion bottles and put in a container, or containers for the day. Ther is no missing of pills if she only remembers to check the container(s), and there she can see how many doses are left and if she needs to take one. I have her setting that up next to her where she works at home, and taking it with her in her purse when she goes out, and next to her bed at night. There is no going to the prescription bottles, everything for the day, and only all that is needed fort the day is already out and handy.
I use a container with seven columns (Sun to Sat) and four rows (Breakfast, Lunch, Dinner, Bedtime). I take my BP, cholesterol, B12, and aspirin at bedtime, so I use the container as a 28 day regimen. I reload it every 28 days. No missed or doubled doses, no opening individual pill bottles, no confusion (did I take my meds already).
That system works real well for me.