Actually that was the start of the Rennaisance in Europe.
I vaguely remember the judged events which historians mark the end of the ‘Middle Ages’ being :
Columbus Sailing for the New World - (to China - he hoped, except there was this continent in the way) 1492
The Fall of Constantinople 1453
Somewhere else I recall a figurative ‘Last Battle Of the Middle Ages’ where the Mamelukes in Egypt tried to fight the French(early Napoleon times)