We take PQQ at 20 mg a day. It helps cause spontaneous generation of new mitochondria in cellseven senescent cells that are thought to be zombie cells. Going much beyond 20 mg a day (maybe to 40 mg, for instance) had some sort of a negative issue I cant immediately recall.
We also take Tru Niagen (nicotinamide riboside), 300 mg/day (one serving is two capsules).
Since changing our regimen a year ago, we feel younger, sleep better, and have a lot more energy, but we also eat a lower (not low, necessarily) carb diet and eat within an eight hour window each day.
Our blood work went from bad to excellent. We both got preferred plus rates on our life insurance, when ten years earlier I was just preferred, yet I felt I was healthier, then with a lot more activity.
Its the length of the supplement list that I fear.
I fear all the supplements adversely effect my prostate.