I find I have issues with my eyes with the LED bulbs. Don’t have the level of annoyance with spiral or incandescent ones.
I believe the LED bulbs technically turn on and off 60 times a second where the persistence of the older ones maintained a constant level of brightness for the eye to experience.
I also see much more disturbing flicker from LED bulbs on a generator than the old bulbs did.
I can sometimes blink and read the wheel patters of cars going 60 MPH. Likewise, I can easily see the blinking of car tail lights - annoying as hell. Obviously I don’t tell my eye doctor, as I prefer to keep my driver’s license.
I haven’t been around residential LEDs enough to notice anything, yet.