[Steely Tom]

This can only work if the particles are “charged up” first. They can’t convert long wavelengths to short wavelengths at ordinary light intensities; sufficient intensity to cause second-harmonic generation would surely be injurious to the eye due to thermal effects.

I very much doubt the Chinese University of Science and Technology has solved that problem, which stems from thermodynamic considerations. If they had, the implications would be extremely wide-ranging, far beyond intra-ocular nanoparticles.

[null and void]

Two photo up-conversion.

[GOPJ]

...sufficient intensity to cause second-harmonic generation would surely be injurious to the eye due to thermal effects. I very much doubt the Chinese University of Science and Technology has solved that problem, which stems from thermodynamic considerations. If they had, the implications would be extremely wide-ranging, far beyond intra-ocular nanoparticles.

What type of implications are you talking about?