yes.
the space suit was invented for u2 pilots
The forerunners of the U2 suits (which only made it to space during the Mercury program, NASA hadn't had time to develop their own) was the suit developed by and for Wiley Post when he pioneered high altitude flight (some more details from Johnson's book, he knew Post) and the Germans' flight suits used for the ME-163B. Those suits were mostly for protection of the pilot in case of a fuel leak, because the fuel dissolved tissues analogously to the way acid does.
David Clarke Company MC-3A lineage suit used in balloon jumps for ejection parachute testing by USAF Captain Joe Kittinger.