I never have used reduced loads in my .44s. Mostly I guess because the powders I use don’t work for them. (H110/W296)
In my 44 loads I also use H110/W296. Dangerous to reduce loads. If I wanted to reduce loads I would use Unique.
I do a lot of 100 yard shooting with my Thompson Contender 44 Mag, 14 inch bbl with 4x scope. It shoots best with heavy bullets and max loads of W296. I can get 1.5” groups, but not with other powders or lighter bullets. My best load so far is with the 265 gr bullets made for the 444 Marlin. I have not tried the Hornaday 300 gr XTP HP yet, but I have some to try.