The whole subject of oxygen availability, hypoxia and cancer fascinates me. Currently they are using injections of drugs like Avastin, an anti VEGF or anti vascular endothelial growth factor to restrict capillary growth, thus restricting nutrients and oxygen to the growing tumor.
Avastin was originally used as an injection in the eye to inhibit the capillary growth leading to wet macular degeneration.
Another theory of cancer that I found interesting, was the mitochondrial theory of cancer.
It proposes that cancer is essentially a mitochondrial disorder, rather than the result of genetic defects in the nucleus of the cell. Experiments have shown, that if you put the nucleus of a cancerous cell into a non-cancerous cell, it remains non-cancerous; but even if you replace the nucleus of a cancerous cell with one from a non-cancerous cell, it remains cancerous.
The application of that theory in practice, is to stave cancer of sugar/glycogen with an extremely low carb ketogenic diet. I read the book Keto for Cancer (https://www.amazon.com/Keto-Cancer-Ketogenic-Metabolic-Nutritional/dp/1603587012/ref=sr_1_3?s=books&ie=UTF8&qid=1529817888&sr=1-3&keywords=keto+and+cancer) and thought that it made a good case.
My friend is on Avastin. She’s in month 14 of glioblastoma. They said her diagnosis was 18 months and it’s looking like that’s going to be exactly right. The tumor growth has slowed, but the progress of her deterioration hasn’t stopped. She seems to age a year every week. These drugs take as much as they give. You live a little longer, calendar wise, but you sleep through most of it, and in the end, it’s like your time on Earth has not been added to, but merely stretched thinner.