[yefragetuwrabrumuy]

In all fairness, Down Syndrome should not be thought of in blanket terms, because there are so many variables, not just to the individual, but to their family.

1) There is a spectrum in Down Syndrome. Not just of the condition itself, which can be mild to severe, but to the associated common conditions, which can have just as much effect on the child’s life, but cannot often be determined before birth, or for long after.

https://www.ndss.org/resources/cooccuring-conditions/

2) If a family has other children, healthy or with other conditions, even if the parents are willing and can afford the extra care for the Down Syndrome child or children; it *will* diminish the care, upbringing and quality of life of the other children. So it is not just the parent’s sacrifice. Not just money, but time, and opportunities for personal enrichment.

3) Institutionalism of a severely handicapped child rarely has positive outcomes. Their quality of life is limited to survival, often with never ending pain and little or no chance for growth. Just slow decline until they die.

4) At the same time, those children with very high functionality Down’s Syndrome may lead near normal and enjoyable lives, with lots of love and care and the attention that children deserve. But this cannot be determined prior to birth.

[New Perspective]

And how do you determine these variables on the womb??? Evidently you have some far superior knowledge than the rest of us.
And DO NOT start your sentence “By all fairness” when your complete tone is leveling acceptance of killing an INNOCENT human being.

[Mrs. Don-o]

These points are, for the most part, realistic, and I think I understand your concerns. However, I would expand on one in order to show a contrast:

You wrote:

2) If a family has other children... it *will* diminish the care, upbringing and quality of life of the other children. So it is not just the parent’s sacrifice. Not just money, but time, and opportunities for personal enrichment.

Many brothers and sisters of Down's children see this in quite a different sense. They might rewrite it thus:

2) If a family has other children... it can increase their capacity for compassion, and an appreciation of simple humanity. Seeing their parents make sacrifices for their "different" sibling will give them the priceless life-experience of knowing what real love is. When they are drawn into being involved in care, they will learn to be caring people. When they see their parents deal with difficulty, they will learn courage.

So it can enrich the "normal" siblings, not with money, but with opportunities for interpersonal depth based on the daily, up-close, hands-on experience of generosity, empathy, patience and hope.

You wrote:

4) But this cannot be determined prior to birth.

I would say this applies to all of life. You do not know if the person you chose to marry will develop a gradual neuro-degenerative disease and you will have to give greater and greater degrees of care to him or her for decades. You do not know if YOU will BE that declining spouse.

You don't know how much care your parents or your spouse's parents will need. You don't know if your great, highly-rewarding, creative important job will cease to exist, dry up and blow away. You don't know if a fire will consume your home and all that you own.

You don't really know what lurks around the corner at the next intersection: and life is full of intersections.

And do you know your purpose in life? Maybe you think your purpose in life is to be healthy, financially secure and have enriching experiences with your attractive wife and two orthodontically perfect and accomplished kids; when actually in God's eyes, your purpose in life is to learn humanity from a child with a misshapen mouth who will never stop drooling.

In an Almighty, Sovereign and Infinite God's eyes, perhaps you are a drooler--- a drooler He loves.