The other side of this coin is the possibility that you will never have grandchildren.
One of my wife's friends has four kids ranging in age from about 39 to 46. None of them are married and none has children. The eldest has decided to go back to school to earn an engineering degree. He is hampered by his lack of algebra skills. The other three have good jobs but little prospect of starting families.
Who wants grandchildren of these self-indulgent, nasty women?