Mental health issues need treatment
Sure they do and they are NOT always treatable and/or curable. Hating one's DNA seems to ME to go way, way beyond the pale.
I doubt if there is a cure for some poor soul who hates his birth DNA so much that he decides to be female.
ANY doctor will tell him/her that s/he will AGE like the baby s/he was born.
DNA does trump everything. :o) Sorry, I couldn't resist. Resistance is fewwwwTILE.