[Rockingham]

Modern flight controls are designed to deal with the loss of a single engine on a twin engine airliner. The FAA even requires certification for ETOPS (Extended range Twin Operations).

The Boeing 787 and 777 are thus certified for up to ETOPS-330, meaning that they can fly for 330 minutes (five and a half hours) on a single engine. The Airbus A330 is certified for 180 minutes of ETOPS flying, and the A350 is pending certification for 420 minutes of ETOPS.

[the OlLine Rebel]

Aware of all the attempts at compensation, but simply stated, losing thrust on one whole side is mechanically unstable. At least with one engine still remaining on one side, there is some thrust created on same wing.