Those of us that work with very large numbers understand how it is not even possible for random changes to DNA to create where we are now. A human DNA strand is estimated to be about 3.2 billion base pairs. That represents a number of (2)^3,000,000,000.
Compare that to the estimated number of atoms in the universe (10)^81
I actually started working on a paper about that. Short version: if every nanometer of the Earth’s biosphere had a strand of DNA of the proper length in it, and every stand underwent one mutation per nanosecond, the time it would take for there to be a 1% chance of arriving at a viable human DNA strand is many septillions (or more) of times longer than the universe has existed.