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If you looked up most drugs the FDA approves you’d flush them too.

ALL OP drugs are Flagged, with Foreto being the highest with a Black Box for Bone Cancer.

Safety update for osteoporosis drugs, bisphosphonates, and atypical femur fractures, A FIB, Jaw Degeneration, Kidney failure deaths. RECLAST is NOT to be given to Asthma patients. It is the worst of the drugs as it NEVER leaves your system.
http://www.fda.gov/drugs/drugsafety/drugsafetypodcasts/ucm229800.htm

Black box warning Foreto
http://www.medicinenet.com/script/main/art.asp?articlekey=21853

OA drugs will ruin your GI Tract, and the PPI will they use to control the GERD it causes will ruin your Bones. Some small studies are cropping up that PPI’s will cause Gastroparesis very painful Slow Motility, and the drugs for it are Black Box labeled and restricted to 12 days.
Neurological side effects that can be permanent. The drug is Reglan. The other drug is Domperidone, and it was Black Boxed in Europe in 2015 for Heart Disease, restricted to 12 days. GP is a life long nasty GI health issue.

These drugs cause ANGER the popular sleep aid Lunesta does.
http://www.livestrong.com/article/167075-what-drugs-cause-aggressive-behavior/

There's not a drug on the market today that doesn't involve a least *some* risk for *some* people.That includes everything from the most cutting edge cancer or heart medication all the way down to aspirin,Mortin and Tylenol.

Next time you develop a life threatening pneumonia try telling the doctor that you're refusing penicillin because you *might* be the 1 in 10,000 people that develop kidney failure because of it.

We're careful about any pharmaceuticals in our family, and Mom was the original standard bearer. I got my first PDR as a college student (that's another story) and had EMT training by then, and have learned a little about medicine since.

With the exception of antibiotics, we believe firmly in the 'least effective dose' of any drug, OTC or prescription, and always read through the possible side effects. Doing so has enabled me to recognize a serum retention toxicity problem with one relative, and an interaction with another (Prednisone/antibiotic) which the doctor had ignored.

Good medicine starts at home, and thankfully we aren't taking any routine medication. When you consider we have eight great-grandkids, we get strange looks from doctors when they ask 'What medication are you taking?" and we tell them "None".