Sorry to nit pick but Congress regulates INTERstate commerce that is between states
Thank you for mentioning that.
Note that I referenced INTRAstate commerce (within a state) as opposed to INTERstate commerce (between states), which is what you mentioned.
In fact, regardless what FDRs activist justices wanted everybody to believe about the scope of Congresss Commerce Clause powers (1.8.3) when they decided Wickard v. Filburn in Congresss favor in 1942, FDRs thug justices wrongly ignored the following imo.
They wrongly ignored that a previous generation of state sovereignty-respecting justices had clarified that the feds have no constitutional justification to stick their big noses into INTRAstate commerce as evidenced by the following excerpt.
State inspection laws, health laws, and laws for regulating the internal commerce of a State, and those which respect turnpike roads, ferries, &c. are not within the power granted to Congress [emphases added]. Gibbons v. Ogden, 1824.