I’ve never liked Charles, and I don’t think the Queen does, much, either. I keep expecting her to abdicate in favor of William. Not far-fetched, I think.
Charles has been a disappointment to a lot of people.
I don’t think she’ll skip Charles. Sally Bedell Smith’s biography of Elizabeth claims that she’s an absolutist when it comes to royal tradition, and wouldn’t consider deviating from the line of succession.
Personally I’d enjoy seeing William crowned, but I think it’s going to be a while before that happens. If the longevity of the Windsors holds true, anyway.