I'm not sure how one does that, but my imagination pictures welder's gloves with wide cuffs and a very large, very thick, beach towel. Probably an extra person, too.
I don't currently have a cat, although I do like them. I won't get one as long as I have my dog because she thinks cats are the most wonderful dog toys ever invented.
When giving a pill to a cat it helps if you have big hands. Put the cat on a table or counter top, hold the cats head with your hand around the back of its head. Put the tip if you thumb and the tip of your middle finger onto the side of the cats head. Begin swaying the cat back and forth to distract it and quickly squeeze the cats jaws to force them open. Then quickly with your other hand put the pill down the cats throat. It helps if you can watch someone else do it first, I told you it was complicated. If you are quick enough the cat doesn’t have time to bite you.