For a utility hem on a cotton shirt, shorts, etc., the best bet is to iron it carefully into place and then stitch it.
By hand always looks best if you are a consistent, patient stitcher -- especially if there is a print and you can pick your way around the colors so your one color thread shows the least. If you want a machine stitch, a regular machine is best, unless you are really good with a hand-held.
Agree. Much easier.