"... the .22 would be my last choice for self-defense.
All other things are not necessarily equal.
... I have relatives, including my father, who no longer shoot anything bigger than .22lr because of health constraints.
There are a whole lot of adequate reasons for compromising on a .22lr,and planning to empty all 8/9/10/12/whatever chambers or a 25 round magazine if needed to stop a threat, given internal or external limitations."
I agree. Well said.
When I was a kid ( mid 60s) my dad had an
Arminius HW7 8 Shot .22 Revolver that was very dependable and accurate.
But I didn't care for the plastic hand grip.
It allowed you the choice of single action or double action, had two cylinders (one for Shorts and Long Rifles, and one for magnums), and had a 6 or 7 inch ribbed barrel.
It was a whole lot of fun.