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Posted on 04/29/2014 6:01:28 PM PDT by Gamecock
The tumor is her tissue. Mutated and reproducing out of control, but still hers.
But the mutation does not enjoy the anti=polio effect from the vaccinations, so is it really here tissue?
That’s what I was thinking.
I guess it took 20 years to figure out how to give it some degree of specificity.
Well, how would someone else’s glioblastoma get in there? It was her tissue. No idea how or why the poliovirus didn’t attack healthy tissue.
Astonishing.
.
Polio attacks the healthy CNS tissue so a modified virus that attacks only mutant tissue isn’t that far fetched.
Absolutely wild idea - and I think I see why this would work.
Vaccinations work by hyping the immune system to attack the thing introduced by vaccination. Since the glioblastoma is in the brain, would the blood brain barrier be holding the immune system back from attacking the polio virus in the brain?
The virus is genetically engineered. Not only does it kill the tumor cells, but is causes the patient's immune system to attack the tumor cells also.
Being vaccinated would mean she produces antibodies to fight the virus. But if you inject the virus directly into the body, you’re asking for a fight, and some healthy tissues would be damaged in the process.
My guess is that the modified virus didn’t attack healthy cells at all. And either she wasn’t vaccinated or the antibodies didn’t recognize the modified virus.
Thanks Gamecock.
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This is amazing news and just brightened my spirits beyond belief.
My mom died of a Glioblastoma multiforme 36 years ago. That they could even diagnos it at they time (those new fangled CT scans) was an amazing plus at the time (the used to “find” brain tumors via xray or post mortum). It was a death sentence...she lived 6 mos and one day (we swear the extra day was her way of flipping off the surgeon who kept casually proclaiming “she won’t last 6 months.) I had found my mom on the kitchen floor (I was in HS). She had had a grand mal seizure.
At the time (again long ago) it was explained to our family they glios grow slowly and once so much of healthy tissue is displaced the “symptoms” start to appear. Amazing to learn that research has brought then to curing happily one patient and I pray ALL others who have this horror.
Thanks for the posting!
It’s not often I can brighten one’s day. Glad I did so for you!
This makes sense because polio is very oriented to attacking the CNS. The real trick is how they modified it to only attack the cancerous tissue.
Future Nobel Prize winners who don't believe in "The Science is Settled"
Actually, those of us who have advanced degrees in subjects like molecular biology, microbiology, etc., have thoughts like that all the time.
;)
Interesting stuff.
I will have to see if this has been published yet in the medical literature, so I can see the exact details of what was done.
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