Even running XP in Win7 has its issues. We do this with a number of PCs at work.
IF you want to sand box (a Win system... always best to sandbox it FROM a Win system.. that way, no worries about drivers/dlls..)...
Running a Win VB in Linux is a real pian, but can be done... I have experienced this prob 2 fold... I have build my own systems since about 1985... all AMD.. AMD isn’t always ‘userfriendly’..