I’m familiar with ketone metabolism. Brains can sustain some of its function on ketone but the body continues to produce glucose even if you consume none. It either converts dietary proteins or starts catabolizing muscle.
Cutting out carbs decreases insulin and other cell growth stimulators, that may explain the relationship between carbs and cancer.
> Brains can sustain some of its function on ketone ...
Humans can live on zero carbs. This has been known since the 1920s. People are now choosing to live in deep NK, and have been, continuously, for years, with no impairment in brain function.
> ... but the body continues to produce glucose even if
> you consume none. It either converts dietary proteins
> or starts catabolizing muscle.
True. Some BG is always there. We can even metabolize it from fat, but at a net energy deficit I imagine.
This residual BG (and the glutamine) is presumably why some R-KD cancer researchers are conjecturing exogenous ketones (BHB and/or AcAc consumed as food) to get ketone levels up to stress the tumors.
> Cutting out carbs decreases insulin and other cell
> growth stimulators, that may explain the relationship
> between carbs and cancer.
I understand that diabetics on metaformin get less cancer. Some folks with cancer are even asking if it might be worthwhile to take metaformin even though they aren’t diagnosed T2D. They may be missing the larger picture.