[dfwgator]

The all-time one, is the toad licking to get high...

I mean somebody had to be the first one who thought to themselves, “Gee, I think I’ll lick this toad.”

[oblomov]

Or self-asphyxiation to stimulate orgasm.

Or how about Alexander Shulgin’s friends who would throw parties to sample phenethylamines that Shulgin had just synthesized in his lab?