I’ve had a number of drug war supporters tell me that we are not a moral people, so the Constitution no longer applies.
What I find amusing is the answers given when you ask the question by what authority does the federal government regulate drugs? Especially given that in order to regulate a particular substance [alcohol] a constitutional amendment was required, which has since been repealed, and no similar amendment exists for drugs.
If I'm feeling particularly clever I'll also show how the War on Drugs is Treason as defined by the Constitution... which, oddly, they never seem to have any counterargument to either.