My point back would be you could say that about any and every game. I have seen some games where a bad call made the difference for a team, it happens, and that's a shame when it does. In this case, it's more than hard to say a call made the difference, 21 points being no where near close enough to make your thesis as true.
Officiating isn't perfect, it's very difficult to get it right all the time in real time, these are games played at lightning speed with incredible athletes. It's amazing the officiating gets it right the vast majority of the time.
That the NFL is happy is irrelevant. The NFL surely would like to have Manning win this coming week as a huge come back story for a great player, do you think the officials knows this, has their orders and will give them the breaks?
I’d rather have the imperfections and get rid of replay, it’s a real power down after a play knowing that it’s going to be another five minutes reviewing the play.