Interesting, ...I have severe insulin resistance, and gout attacks at least once a month, presently in both feet, and my fructose intake has been next to zero for decades now. The last time I ate something with fructose in it was about four months ago, a doughnut and small glass of milk to offset low blood sugar. I was too weak to get out of my chair. If the damage is offset by ceasing to eat fructose, or fructose products, I wish it would start getting offset in me. About fourteen years ago I had a colon resection, and the doctor went over every inch of my liver. He said it looked perfect and healthy.
I don’t doubt the validity of this research. We all know fructose is the real villain in type 2 diabetes, but it would seem some livers have the ability to produce copious amounts of fructose without any help. Not even large doses of Metformin turns mine off. ...A strict Akins diet, with limited calories works to lower my blood sugar, but my uric acid levels go through the roof.
The type of gut bacteria one has may be an important influence.