Imagine having a drone that only needs to land to change the bearings and get a lube job!
I think more about a "container ship" version about the size of the carrier Enterprise or larger. Direct from China to any major city. Probably with 100-1000 individual LENR reactors and gas cells. Massive redundancy. Much faster and probably much cheaper (and safer) than any cargo ship.
The dockworkers and port cities will hate it.
But your vision is also correct. It doesn't have to be rocketry or jet speeds to be useful aeronautically.