I took Cymbalta for a couple of years to help with post surgical neuropathy - Lyrica and Gabapentin did little to ofer any relief.
I can say that they helped A BIT. I could notice a difference in discomfort level after being on Cymbalta for about a month. That said, I will never do it again. The horrid experience, for me, was getting off Cymbalta. Even following a rigid titration schedule to reduce the dosage left me with unbearable side effects, the worst of which was “brain tremors” - Yes, brain tremors!
Also called brain zaps and brain shivers, though I thankfully didn't ever experience them.