A real deal-breaker for anyone are the sharply checkered grips common on older handguns. Even shooting a .380 can get tedious if the grips are biting. I mind shooting a checkered .38 far more than shooting a smooth .45. I guess you eventually get used to it, or get gloves.
Agree. And that reminds me to mention that it's best to start shooting with a low recoil gun to learn safety and accuracy first.
My step dad started me at 10 years old with a 12 GA Browning semiauto skeet gun that kicked like an Army mule. I developed a flinch because of the kick. Some smart instructors would load my gun with duds to see how smooth my action was - almost always reacted to whatever punishment I thought I'd take from the gun (but managed to still hit my target with a real bullet somehow).