Not So most are potent far beyond their expiration dates:
http://www.terrierman.com/antibiotics-WSJ.htm
An important anti biotic Doxycycline is synthetic Tetracycline. Its however becomes quite toxic when it expires or if stored improperly. It is important to rotate your stock and discard the out of date stuff.
My doctor gave me scripts for Cipro, said stored in the refrigerator it would keep almost indefinitely. Said it was one of the best broad spectrum to store for this purpose.
He also had me get some prescription antibiotic ointment for use with MRSA infections. That is also now stored in the frig.
And ALWAYS keep a 12 month supply of any essential medicines you have to take. If you have to pay more to get the quantity because insurance will only cover 30 days at a time, tough, spend the money and do it. I have 18 months of my heart meds, and I keep it at that level. Ditto for the wife’s BP meds.