Usually but not always...depends on her age, how long she was fat, and how fast she took it off. The biggest problem that people have with loose skin is they take off the weight too fast.
There are multiple ways to minimize and avoid loose skin but in some cases with super obese it's near impossible to avoid.
I have seen men and women lose that kind of weight and not have severe loose skin issues.
My fault. I doubled her weight loss. Big difference between losing 200 pounds and 100 pounds.