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To: cycjec; Gay State Conservative

I wonder if this medicine ‘covers’ receptors in the brain to prevent the desire to consume alcohol, similar to how Methadone/Buprenorphine works for folks who are addicted to Opiates. Either way, I hope it works out.


5 posted on 08/28/2012 2:47:13 PM PDT by KoRn (Department of Homeland Security, Certified - "Right Wing Extremist")
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To: KoRn
I wonder if this medicine ‘covers’ receptors in the brain to prevent the desire to consume alcohol, similar to how Methadone/Buprenorphine works for folks who are addicted to Opiates. Either way, I hope it works out.

Yeah, exactly. It hits an inhibitory neurotransmitter called GABA b, modulating it, and thereby increasing its relaxing effects upon the autonomic nervous system.

Acts on a different receptor site from Opiate-like drugs, though, which I think hit dopamine sites.

8 posted on 08/28/2012 3:12:45 PM PDT by Dysart (Id like to look it in the eye but there is no eye)
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To: KoRn
I wonder if this medicine ‘covers’ receptors in the brain to prevent the desire to consume alcohol, similar to how Methadone/Buprenorphine works for folks who are addicted to Opiates.

Seems distinctly possible.An example of what you're suggesting...in addition to having seen alcohol's devastation during my tenure at the hospital I also saw many,many heroin OD's.Part of the standard treatment for these OD's was the immediate administration of an opioid antagonist medication called naloxone.Shortly after administration the patient,who about 30 seconds earlier was clinically dead,was up,talking and usually demanding to leave.A true miracle drug.Just one of the examples that I've seen of what an amazing thing the human brain is.

9 posted on 08/28/2012 3:16:44 PM PDT by Gay State Conservative (Voter ID Equals "No Representation Without Respiration")
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