If an armed perpetrator was running away from me and toward my daughter's bedroom, I would empty my gun into his back as fast as I could. If he was still standing, I would reload and shoot some more.
Just because a person shows you his back does not mean that he is surrendering, that he has given up attacking you, or that he is no longer a danger to you.
That is a whole different scenario, my FRiend.
And a 10mm is deadly, in a bad way.