Any antivirus program you use will occasionally miss stuff. Pick the best workhorse you can find and then periodically go to an online site for one of the AV vendors and run their usually free one-time check. TrendMicro is especially good for this. McAfee, Norton and BitDefender are all good within their limits, but they don’t check for older viruses (greater than 2 or 3 years), they can’t or that’s all your PC would ever do.
The TrendMicro House Call makes you download a small kernel and then then it checks you system for everything, including stuff that might be 5, 6, or more years old.
And it finds them.
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