You can use the larger/smaller buttons to change size. Disappearance persists up to surprisingly large sizes.
You can use the back-col button to change the background colour. The yellow dots disappear into whatever colour the background has.
The defaults button at the top restores the standard settings.
According to Michael Bach, "Steady fixation favours disappearance, blinks or gaze shifts induce reappearance. All in all reminiscent of the Troxler effect, but stronger and more resistant to residual eye movements."
Blinking your eyes stops this. Learned early in flight training.
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Well known effect in the target shooting community. You have about 20 seconds from the time of target acquisition to shoot. After that, your sight degrades rapidly.