[mamelukesabre]

so...being fat increases risk of dementia?

[madison10]

so...being fat increases risk of dementia?

I wouldn't automatically draw that conclusion. The hormone is in fat, but does everyone have the hormone? I've read that when a person is going into dementia/Alzheimer's he or she loses a great deal of weight in a short period of time.

The people I know that have Alzheimer's come in all shapes, sizes, and sexes.

[hellbender]

I think it was already known that obesity increases the risk of Alzheimer's:

http://www.webmd.com/alzheimers/guide/20061101/obesity-alzheimers-risk

[CaptainK]

"Different people have different metabolic set points and that can change over the lifespan," said Dr. Samuel Gandy, professor of Alzheimer's disease research at Mount Sinai School of Medicine. "In one group, you have midlife obesity leading to late-life complications; in another group, there might be not obesity but instead late life weight loss, and that can also lead to complications."."

I think the article is saying this hormone can change the metabolism to increase or decrease fat to an unhealthy level and both scenarios can lead to dementia.

[the OlLine Rebel]

I don’t think that’s the bottom line. Likely it’s mostly that women have more body fat by nature, and have this hormone in it. They mention men but don’t have enough empirical study on it.

[editor-surveyor]

>> “so...being fat increases risk of dementia?” <<

.
No.

Insulin resistance increases risk of dementia, and of weight gain also. (IOW “Type II diabetes” causes both +/-)