The Interior Department put out a warning a couple of years ago. Though normally enemies, a cross-bred wolf and coyote had been sighted in New England. They decided that the mixed intelligence of the two was so dangerous that they should be shot on sight. Someone said it was like “the canine equivalent of a leopard.”
There are some unconfirmed reports of Coy-dogs in the Chicago suburbs. If true those will be some extremely dangerous critters.