If I were going to spend the rest of my life hunting Coyotes and could choose any gun ammo scope etc. withing reason it would be:
A Colt AR-15 H-BAR with a 3X9 Leupold or even a 4X Leupold. I would shoot commercial .223 55 grain hollow point boat tails.
I could get by just fine with a rifle I once had. It was an H&R Handi-gun in .357 maximum. It was a break barrel single shot and I was not expecting it to be accurate but it turned out to be a great shooter, more accurate than most of my bolt actions. That .357 Maximum with a 158 grain jhp out of the 22 inch barrel was hot, quite a bit hotter than a 30-30. Than main thing is it was light and carried like a dream.
Another possibility would be one of the HK .22 magnum auto loaders. They are probably getting hard to find but were uncommonly accurate.