If you can still remember to. ;-)
No. If you keep your skillet properly cured, and use enough fat during cooking, the food should never touch iron.
I use a good non-stick skillet, because I'm too lazy to properly care for cast iron.
Possibly the best skillets are cheap steel. Inexpensive, so quickly wearing-out doesn't matter. Steel also is harder, so shouldn't shed it's components into the food.