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Not to be confused with cotinin.

Cotinine Systematic (IUPAC) name (5S)-1-methyl-5-(3-pyridyl)pyrrolidin-2-one Identifiers CAS number 486-56-6 ATC code None PubChem CID 854019 ChemSpider 746405 Yes UNII K5161X06LL Yes ChEMBL CHEMBL578211 Yes

Cotinine is an alkaloid found in tobacco and is also a metabolite of nicotine.[1][2] The word "cotinine" is an anagram of "nicotine". Cotinine is used as a biomarker for exposure to tobacco smoke and has also been sold as an antidepressant under the brand name Scotine.[1]

Similarly to nicotine, cotinine binds to, activates, and desensitizes neuronal nicotinic acetylcholine receptors, though at much lower potency in comparison.[2][3][4][5] It has demonstrated nootropic and antipsychotic-like effects in scientific research.[6][7]

http://en.wikipedia.org/wiki/Cotinine

1 posted on 04/27/2011 7:52:48 AM PDT by decimon

To: neverdem; DvdMom; grey_whiskers; Ladysmith; Roos_Girl; Silentgypsy; conservative cat; ...

2 posted on 04/27/2011 7:53:41 AM PDT by decimon

Unless they can create a product to be patented, this cure won’t see the light of day.

4 posted on 04/27/2011 8:05:26 AM PDT by aimhigh (True bitter clingers cling to their guns AND their bibles.)

I finally quit chewing tobacco after 30 years. put on 30 lbs. and now I can’t remember s**t.

7 posted on 04/27/2011 8:22:01 AM PDT by deweyfrank

10 posted on 04/27/2011 9:08:17 AM PDT by DJ MacWoW (America! The wolves are at your door! How will you answer the knock?)

Woo-hoo! Feels like a night to break out the pipe and enjoy a good smoke...And maybe some good scotch as well...

11 posted on 04/27/2011 10:05:45 AM PDT by opus86

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