Physiological insulin resistance is when there’s a lot of saturated fat floating around. The muscles and other tissue which are capable of using fat as a source of energy become insulin resistant in order to spare glucose for the brain, which can’t use fat.
The reason is that when your glycogen stores run out, the brain has to run on glucose produced by the liver, and the muscles and most other tissue can run on fat, so they spare the glucose for the brain.
The same thing will happen if you eat a high fat and high carb meal, but the carb absorption is somewhat slowed by the fat, so it’s not that bad.
Pathological insulin resistance is what tested by a glucose tolerance test, and the fasting glucose.
The GTT is basically feeding 75g or so of sugar/carbs (no fat) and then measuring blood glucose. If it’s high, this means that your body is insulin resistant despite the lack of fat in your bloodstream.
Similar for the fasting glucose. After fasting overnight, you’re probably done digesting the food, so it will measure the glucose level needed to feed your body.
A high triglyceride level is also related to insulin resistance ...
Does that make sense ?
Thanks!
Interesting. I have “syndrome x” and pcos. And now D2. VERY insuling resistant. I’m marking this to read tomorrow when I’ve not had to take a pain pill, lol.
Syndrome X - strike 1
pcos - strike 2
severe asthma - strike 3
I’m OUT!