I second the NZ Green Lipped Mussel. It was an arthritis research break through when I was living in NZ about a decade ago and the research was done on dogs. I’ve found very few know about it in the U.S. I later had a German Shepherd discovered to have bad hips. The vet recommended 3 Green Lipped Mussel capsules a day. The dog had a very noticeable limp. I swear, the limp was gone in under a week! I had a bad knee I took glucosamine and chondroitin for and it didn’t help. After the mussel worked so well for the dog, my husband and I tried it. In just a couple days I noticed a big improvement and was pain free in about a week. Two weeks ago I shipped my husband about a 6 month supply since he’s been in and out of the country. He starts to notice a difference if he’s off it a while. I buy “Sea Mussel” by “Now” from Amazon. It’s reasonably priced. When I searched online years ago, there were a lot of companies trying to capitalize on the “New Zealand” tag and make big bucks. I also never have problems with it repeating on me and tasting mussel all day like some other products I’ve tried. I hope this info. helps.
Thank you for the “Now” recommendation for NZ Green Lipped Mussel. Gonna give that a go next payday!
The vet stopped short of telling me it would repair damage already done, but I believe it did so for both me & the dog for the time I was buying it.
http://www.amazon.com/s/ref=nb_sb_noss?url=search-alias%3Dhpc&field-keywords=sea+mussel&x=8&y=17
Note to the OP, I dunno if the mussel can help against the extremes you posted about, but I highly recommend it for any issues involving missing/damaged cartilage.