My kids do it all the time. I run Windows programs under Fedora also.
I had no idea. I created an “ubuntu” disk once, but it ran so slow on my machine that I dumped it. I also used open office on my wife’s vista laptop but the whole thing stopped working. None of the internal apps would recognise text entry. I even deleted and re-installed from the latest version. No luck.
So I bought Office 2007.
There are a lot of things I like about Linux, but it is still not my primary desktop. I just have too many Windows programs I need in my job that have no Linux equivalent, and not all Windows programs will run under Wine.
This is just another "Linux is better than Windows" threads. In many ways, that statement is true, but until you get the level of software support (application development and support) available under Linux that you have for Windows, Linux will not be a serious challenger for the enterprise desktop. And once you do get that level of software support, you will lose a lot of the "free" nature of Linux that makes it so appealing.