I’m self-employed and sitting in my home office using a desktop. There is no way I could ever use a mobile device for all my business applications including updating & maintaining my website, Excel spreadsheets, large Word docs, marketing brochures, business email, PDFs, SKYPE to communicate with my Euro and Far East partners, etc.
Never say never, you will eat your words.
See # 20. When I swapped my Apple //GS for a Mac, I did so for a "mobile device" -- and I have owned and used nothing else ever since.
Right now, I defy you to show me a job I can't do superbly well on my MacBook Pro (with external displays, etc...).
And, in case you haven't looked up and taken notice, technical innovation ain't standing still!
>>>...SKYPE to communicate with my Euro and Far East partners, etc.
You can Skype on several Verizon cell phones...