I have Windows XP, which has a pretty good Task Manager. I just hit ctrl-alt-del as soon as possible, selected the task manager, scrolled down to highlight XXXXsysguard.exe, and selected "End process". I think I may have had to do it twice. It's a race against time, so be sure to stay cool, calm, and collected as you fumble around :-)
When I put the thumbdrive in, with the SUPERAntiSpyware on it, I used Windows Explorer ( not Internet Explorer! ) to run it, and as I said, it seemed to go very smoothly from there, ( not forgetting about unsetting "Proxy Server" in IE! )
I think my Safe Mode boot problems may have been because I put the thumbdrive in before the boot. It may look there for a boot image, or something.
@dr_lew: Thanks for the advice....I am now posting from my previously infected PC. Best Buys wanted $200 for what you and other Freepers helped me do in about an hour. But I did kind of back into the “fix”. Like you I put the flash drive with the downloaded program in before I started the “safe mode” start-up. Then I couldn’t get out of “safe-mode” without going through the “restore” process. I restored to a date prior to the trojan/virus showing up and everything is now fine. I guess there’s more than one way to “skin a rabbit”. Since I am pretty computer/software illiterate I am pretty darn proud of myself today. Thanks again for starting this thread.