I would have no problems with them separating.
I always hold open the option for reconciliation among marriage partners.
Remember that ad campaign? Little white boy..."I am Tiger Woods". Little asian girl..."I am Tiger Woods". Grown hispanic man..."I am Tiger Woods".
How true that is...spiritually. We are all a decision away from completely ruining everything that matters and we hold dear. Lots of glee and bashing for this "Man at the well".
I don't claim to have it handled, but many people forget to look at things through a filter of Grace. Without Christ, I have no idea what I would have put my wife through.