Fluorescent puppy is world's first transgenic dog

newscientist ^ | 23 April 2009 | Ewen Callaway

[JoeProBono]

A cloned beagle named Ruppy – short for Ruby Puppy – is the world's first transgenic dog. She and four other beagles all produce a fluorescent protein that glows red under ultraviolet light. A team led by Byeong-Chun Lee of Seoul National University in South Korea created the dogs by cloning fibroblast cells that express a red fluorescent gene produced by sea anemones. Lee and stem cell researcher Woo Suk Hwang were part of a team that created the first cloned dog, SnuppyMovie Camera, in 2005. Much of Hwang's work on human cells turned out to be fraudulent, but Snuppy was not, an investigation later concluded. This new proof-of-principle experiment should open the door for transgenic dog models of human disease, says team member CheMyong Ko of the University of Kentucky in Lexington. "The next step for us is to generate a true disease model," he says.

[JoeProBono]

[Cvengr]

I was wondering why my bulgogi was glowing the other night.

[Blogger]

I hate this. Science is delving into areas just for the heck of it and doesn’t have a clue or care what Pandora’s box they are opening up.

[bolobaby]

And this experiment is helpful because....?

[MyTwoCopperCoins]

Because if you can transplant genes, it would become possible to share advantageous features of genetics across the species barrier. It could be immunity to certain diseases, diabetes, heart disease, or eugenics, etc.

[LongElegantLegs]

No more tripping over the chihuahua during the night!

[JoeProBono]

[exDemMom]

In part, because it gives a way to “tag” a gene to make it visible without harming the animal. The research potential of the technique is limited only by the researchers’ imaginations. So much of animal research depends on having to sacrifice the animal at some point during the experiment; a technique like this makes it possible to make the observations without sacrificing the animal. Plus, observations of a couple animals over time are far more valuable than observations of several animals at a single time point.

I could go on and on about this, so I will stop now and spare everyone the wall of text.

[DeLaine]

This would have worked really great when I raised our guide dog pup.
He was a black Lab and I live way out in the country, and moonless nights are DARK.
For the first weeks after he arrived, when I’d take him out to do his business at night, I could not see him at all and would be bending down to try to see his outline against the pale siding of our house, so I could tell when he was going.
hoot

[Allegra]

Glo-Puppy ping.

Also an AAAWWWWWWW ping.

[shibumi]

"And this experiment is helpful because....?"

So that if you're eating in a Korean Techno-Rock nightclub, you can see the meat in your soup.

[AUH2O Repub]

In part, because it gives a way to “tag” a gene to make it visible without harming the animal. The research potential of the technique is limited only by the researchers’ imaginations. So much of animal research depends on having to sacrifice the animal at some point during the experiment; a technique like this makes it possible to make the observations without sacrificing the animal. Plus, observations of a couple animals over time are far more valuable than observations of several animals at a single time point.

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I hope you are kidding, are you also in favor of killing babies for their stem cells? This messing with genetics like this is the road to hell. Where do you think this is going to lead to? Do you think these "researchers" will stop with puppies? Someone already said they have cloned humans. We have to stop these people from trying to play God. There will be serious consquences.

[USMCWife6869]

Doggie Ping

No need for pics, you posted them already :)

[trisham]

Interesting. Thanks.

[trisham]

What adorable puppies!

[JoeProBono]

[JoeProBono]

Oops

[Jeff Chandler]

Glow Pups

[MyTwoCopperCoins]

LOL, probably all the carbohydrates that you eat, are sourced from genetically modified plants.

[trisham]

LOL! That is so cute!