After testing a new drug in clinical trials among hundreds or thousands of people, and then gaining FDA approval, the drug moves to the full market where millions of people have access to it. Some people think that adding millions of customers for a product as complex as a pharmaceutical should produce the same results as found in the clinical trials. These are also the same people who think all risk can be removed from our lives with enough regulation and oversight. They don't understand much about science or research.
Bringing a NME to market, from discovery to approval, can take more than 12 years and can cost up to $800 million. IIRC, only about 1 in 4,000 drugs proposed in preclinical testing actually ever makes it to market. Anyone who thinks the relationship between industry and the FDA is anything but adversarial has no idea what they're talking about.
But what’s really amazing is that these same quacks will imediately the source herb of said drug with no demonstrated efficacy, no safety tests, no purification, and if the government notices that people are dying from the nonsense, they’re “jack-booted thugs.”