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Download, update and scan your computer with Malwarebytes and SuperantiSpyware, delete what ever they find, if this fails to completely remove the infection download then update Avast and run a boot scan (click schedule boot-time scan and restart your PC), all the software below is completely free and safe to use.

If your infection is proving hard to remove run SmitfraudFix following the guide below.

Malwarebytes: http://www.malwarebytes.org/mbam.php

SuperantiSpyware: http://www.superantispyware.com/

Avast Anti-Virus: http://www.avast.com/eng/avast_4_home.ht...

SmitfraudFix: http://siri.geekstogo.com/SmitfraudFix.e...

Guide to using SmitfraudFix: http://www.bleepingcomputer.com/forums/t...

To protect your PC in the future you need to use anti-virus software and a firewall, id recommend using Avast and Comodo Pro firewall both are very effective and completely free, you should also switch to Firefox 3 if you are browsing with IE as its much safer.

Also, Spybot Search and Destroy will get it without a problem (I use it a lot).

Lastly, download HIJACK THIS run it first to log the registry and boot info for stuff running. After the PC appears to be clean, run HiJack this again and compare the 2 logs making sure not to have assigned the logs the same name.

If you are not got with this operation, find a friend who knows a little.