[SampleMan]

Spoked wheels most closely resemble "Perimeter Box" construction, which always results in the highest strength to weight ratios, materials being equal.

Yes, strength to weight ratio is excellent, but the tensil strength is carrying most of the load, as the compressed spokes will easily buckle. But it isn't the static weight that is the problem for the spoked wheel, it is handling the drive loads of turning the wheel from the hub, which asks a lot more in tensil strength. Which is why its not uncommon to see a solid wheel in back and a spoked wheel in front.

[SENTINEL]

When looking from the side the spokes exit close to tangentially from the hub and then mate perpendicularly to the rims.

It's a good thing harley riders cannot corner quickly, all that weight along with road induced g forces at the edge of those wide tires would create quite a bending moment.